Acrylic anhydride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Acryloxide, Prop-2-enoyl prop-2-enoate, Acrylic acid anhydride
Non-Fluorochemicals, API & Intermediates
KUMI0F1020
2051-76-5

PubChem ID

Reax
MFCD00048146

PubChem ID
74919
1747004
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
Acrylic anhydride
C6H6O3
126.11
≥98%
Colorless to LightYellow Liquid
120-125°C/5 mmHg
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
Acrylic anhydride (also known as Acryloxide, Prop-2-enoyl prop-2-enoate, Acrylic acid anhydride) is typically used to prepare specialty acrylate, acrylamide monomers or acrylic resin. One recent example is that it can be used in the synthesis of LOU064 (remibrutinib), a potent, highly selective covalent BTK inhibitor.
ROS-Activated Ratiometric Fluorescent Polymeric Nanoparticles for Self-Reporting Drug Delivery. [1]
Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase. [2]
References:
[1] M.Zhang, et al, ACS Appl. Mater. Interfaces, 2018, 10(9), pp 7798-7810.
[2] D.Angst, et al, J. Med. Chem., 2020, 63(10), pp 5102-5118.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H317,H319,H335
P280,P301+P312+P330, P302+P352,P305+P351+P338
29161995
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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