Ethyl 2-(3-chloro-5-cyanophenoxy)acetate is an ethyl ester intermediate typically used in the prepartion of MK-1439 as a non-nucleoside reverse transcriptase inhibitor in the treatment of HIV/AIDS.
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses. [1]
Highly efficient synthesis of hiv nnrti doravirine. [2]