Ethyl 2-(3-chloro-5-cyanophenoxy)acetate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN

Nonfluorochemicals, API&Intermediates
KUMI0F255
1613307-27-9
 
 
26926788 
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Ethyl 2-(3-chloro-5-cyanophenoxy)acetate
C11H10ClNO3
239.66
≥98%
White to Yellow Solid
41-42°C
5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
Ethyl 2-(3-chloro-5-cyanophenoxy)acetate is an ethyl ester intermediate typically used in the prepartion of MK-1439 as a non-nucleoside reverse transcriptase inhibitor in the treatment of HIV/AIDS.
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses. [1]
Highly efficient synthesis of hiv nnrti doravirine. [2]
References:
[1] B.Cote, et al, Bioorg. Med. Chem. Lett., 2014, 24(3), pp 917-922.
[2] D.R.Gauthier, et al, Org. Lett., 2015, 17(6), pp 1353-1356.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933998090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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