Methyl-d3-amine hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Deuterated methylamine hydrochloride, Methyl-d3-ammonium chloride
Non-Fluorochemicals, API & Intermediates
KUMI0F1013
7436-22-8

PubChem ID

Reax
MFCD00064559

PubChem ID
2723974
4140467
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Methyl-d3-amine hydrochloride
CH6ClN
70.54
≥99%
White to Off-White Solid
232-234°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
Methyl-d3-amine hydrochloride (also known as Deuterated methylamine hydrochloride, Methyl-d3-ammonium chloride) is an intermediate typically used in the preparation of BMS-986165, a highly potent and selective allosteric inhibitor of TYK2.
Quantitative liquid chromatography-electrospray ionization-mass spectrometry analysis of amine-containing metabolites derivatized with cyanuric chloride and methylamine isotopologues. [1]
Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis. [2]
References:
[1] D-Y.Lee, et al, J. Chromatogr. A, 2015, 1388, pp 60-68.
[2] K.Papp, et al, N. Engl. J. Med., 2018, 379(14), pp 1313-1321.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P302+P312,P305+P351+P338
28459010
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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