N-Cyanoacetylurethane is a heterocyclic intermediate that typically used in the preparation of MGL-3196 as a potent and highly selective thyroid hormone receptor β agonist for the treatment of dyslipidemia.
Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196,a liver-targeted thyroid hormone receptor-β agonist. Atherosclerosis. 
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia. 
 R.Taub, et al, Atherosclerosis, 2013, 230(2), pp 373-380.
 M.J.Kelly, et al, J. Med. Chem., 2014, 57(10), pp 3912-3923.
NONH for all modes of transport
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