N,O-Bis(trimethylsilyl)acetamide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
BSA
Non-Fluorochemicals, Trimethylsilylating agents
KUMI0F202
10416-59-8
MFCD00008270
6913588
2206090
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
N,O-Bis(trimethylsilyl)acetamide
C6H15NOSi
145.28
≥98.0%(GC)
Colorless to Pale Yellow Liquid
164-166ºC
5g,10g,20g,50g,100g,500g,1kg, 25kg and 50kg
Store under argon
N,O-Bis(trimethylsilyl)acetamide (synonym: BSA) is a powerful and commonly used trimethylsilylating reagent for GC derivatization and silylation of a wide range of acidic functional groups, such as non-sterically hindered alcohols,amides,amines,aminoacids,carboxylic acids and enols. Its silylating potential is similar to that of BSTFA and MSTFA and more potent than HMDS or TMSDEA, depending on the conditions and substrates used.
Quantitative gas-liquid chromatography of sulfur containing amino acids. [1]
Protection for the Hydroxyl Group, Including 1,2‐ and 1,3‐Diols. [2]
References:
[1] F.Shahrokhi, et al, J. Chromatogr., 1968, 36(1), pp 31-41.
[2] P.G.M.Wuts, et al,  Greene’s Protective Groups in Organic Synthesis, 5th ed., New Jersey, 2014, Chap. 2, 17.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H226,H302,H314
P280,P305+P351+P338,P310
2931900090
UN 2920 3(8)/PG II

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