Tetrahydroxydiboron

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Hypoboric acid,Diboronic Acid,Bis-Boric acid,Tetrahydroxydiborane,BBA
Non-Fluorochemicals, Borylating Reagents
KUMI0F80
13675-18-8

PubChem ID

Reax
MFCD05663888

PubChem ID
10986154
14723923
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Tetrahydroxydiboron
B2H4O4
89.65
≥98%(HPLC)
White to Off-white Solid
290°C
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at room temperature
Tetrahydroxydiboron (also named as Hypoboric acid,Diboronic Acid,Bis-Boric acid,Tetrahydroxydiborane,BBA) is an efficient borylating reagent which can be used to borylate a wide variety of aryl and heteroaryl substrates with low Pd- and Ni-catalyst loads.
Palladium Pincer Complex Catalyzed Substitution of Vinyl Cyclopropanes, Vinyl Aziridines, and Allyl Acetates with Tetrahydroxydiboron. An Efficient Route to Functionalized Allylboronic Acids and Potassium Trifluoro(allyl)borates. [1]
Palladium-Catalyzed, Direct Boronic Acid Synthesis from Aryl Chlorides: A Simplified Route to Diverse Boronate Ester Derivatives. [2]
Nickel-Catalyzed Borylation of Halides and Pseudohalides with Tetrahydroxydiboron [B2(OH)4]. [3]
Rapid and Selective in situ Reduction of Pyridine-N-oxides with Tetrahydroxydiboron. [4]
Tetrahydroxydiboron-Mediated Palladium-Catalyzed Transfer Hydrogenation and Deuteriation of Alkenes and Alkynes Using Water as the Stoichiometric H or D Atom Donor. [5]
References:
[1] S.Sebelius, et al, J. Am. Chem. Soc., 2005, 127(30), pp 10478-10479.
[2] G.A.Molander, et al, J. Am. Chem. Soc., 2010. 132(50), pp 17701-17703.
[3] G.A.Molander, et al, J. Org. Chem., 2013, 78(13), pp 6427-6439.
[4] A.T.Londregan, et al, Synlett., 2013, 24(20), pp 2695-2700.
[5] S.P.Cummings, et al, J. Am. Chem. Soc., 2016, 138(19), pp 6107-6110.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302+H332,H315,H319,H335
P261,P301+P312+P330,P305+P351+P338
2810009000
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.