(R)-(-)-3-Amino-1-Boc-piperidine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
Non-Fluorochemicals, API & Intermediates
KUMI0F980
188111-79-7

PubChem ID

Reax
MFCD03094717

PubChem ID
1501974
10662512
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
(R)-(-)-3-Amino-1-Boc-piperidine
C10H20N2O2
200.28
≥98%
Colorless to Light Yellow Liquid
 
10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
(R)-(-)-3-Amino-1-Boc-piperidine (also named as (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate) is an intermediate typically used in the preparation of various pharmaceutically avtive substances, e.g. Dipeptidyl Peptidase IV inhibitors, Bruton tyrosine kinase (BTK) inhibitors, and so on.
Synthesis and evaluation of nicotinamide derivative as anti-angiogenic agents. [1]
A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit. [2]
Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. [3]
Radiosynthesis of a Bruton's tyrosine kinase inhibitor, [11 C]Tolebrutinib, via palladium-NiXantphos-mediated carbonylation. [4]
References:
[1] H-E. Choi, et al, Bioorg. Med. Chem. Lett., 2013, 23(7), 2083-2088..
[2] J. Wang, et al, J. Biol. Chem., 2015, 290(48), pp 28834-28846.
[3] T.A. Popp, et al, J. Med. Chem., 2016, 59(19), pp 8889-8912.
[4] K. Dahl, et al, J. Labelled Comp. Radiopharm., 2020, 63(11), pp 482-487.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
29333999
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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