tert-Butyl 3-trans-aminocyclobutane-1-carboxylate (also named as trans-1-Boc-3-aminocyclobutane)is a chiral intermediate typically used in the prepartion of PTI-428, which is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier.
Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. [1]
