tert-Butyl 3-trans-aminocyclobutane-1-carboxylate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
trans-1-Boc-3-aminocyclobutane
Nonfluorochemicals, API&Intermediates
KUMI0F242
1192547-86-6 
MFCD16661182
53308458
 
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
tert-Butyl 3-trans-aminocyclobutane-1-carboxylate
C9H17NO2
171.24
≥98%
White to Yellow Solid

5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
tert-Butyl 3-trans-aminocyclobutane-1-carboxylate (also named as trans-1-Boc-3-aminocyclobutane) is a chiral intermediate typically used in the prepartion of PTI-428, which is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier.
Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. [1]
Reference:
[1] M.Mijnders, et al, Curr. Opin. Pharmacol., 2017, 34, pp 83-90.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338,P302+P352
2922498590
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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