tert-Butyl (3S)-3-methylpiperazine-1-carboxylate is a chiral intermediate that commonly in the preparation of various pharmaceutically active compounds, e.g. AMG-510 as a potent KRAS G12C covalent inhibitor for the treatment of a number of disorders, including pancreatic, colorectal, and lung cancers.
Benzamide capped peptidomimetics as non-ATP competitive inhibitors of CDK2 using the REPLACE strategy. 
KRAS G12C INHIBITORS AND METHODS OF USING THE SAME. 
INHIBITORS OF KRAS G12C AND METHODS OF USING THE SAME.