tert-Butyl (3S)-3-methylpiperazine-1-carboxylate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(S)-4-N-Boc-2-methylpiperazine
Nonfluorochemicals, API&Intermediates
KUMI0F272
147081-29-6
MFCD02683204

Rea
7023035

Reax
8978098
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
tert-Butyl (3S)-3-methylpiperazine-1-carboxylate
C10H20N2O2
200.28
98%
White to Yellow Solid
35°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperture
tert-Butyl (3S)-3-methylpiperazine-1-carboxylate is a chiral intermediate that commonly in the preparation of various pharmaceutically active compounds, e.g. AMG-510 as a potent KRAS G12C covalent inhibitor for the treatment of a number of disorders, including pancreatic, colorectal, and lung cancers.
Benzamide capped peptidomimetics as non-ATP competitive inhibitors of CDK2 using the REPLACE strategy. [1]
KRAS G12C INHIBITORS AND METHODS OF USING THE SAME. [2]
INHIBITORS OF KRAS G12C AND METHODS OF USING THE SAME. [3]
References:
[1] P.N.Premnath, et al, Bioorg. Med. Chem. Lett., 2016, 26(15), pp 3754-3760.
[2] B.A.Lanman, et al, US2018/334454 A1.
[3] B.A.Lanman, et al, US2019/77801 A1.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H318,H335
P261,P280,P305+P351+P338
2933599590
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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