tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
4-Boc-4,7-diazaspiro[2.5]octane
Nonfluorochemicals, API&Intermediates
KUMI0F293
674792-08-6
MFCD08685932

Rea
51358567

Reax
14324170
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate
C11H20N2O2
212.29
98%
White to Off-white Solid

5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperture
tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate is a heterocyclic intermediate that typically used in the preparation of RG7916 as a selective survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the treatment of spinal muscular atrophy (SMA).
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs. [1]
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA). [2]
References:
[1] A.Poirier, et al, Pharmacol. Res. Perspect, 2018, 6(6):e00447.
[2] H.Ratni, et al, J. Med. Chem., 2019, 61(15), pp 6501-6517.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933998090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.