1-hydroxymethyl-1-(trifluoromethyl)cyclobutane

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(1-(trifluoromethyl)cyclobutyl)methanol
Trifluoromethyl Building Blocks
KUMI3F75
371917-16-7
MFCD28383968
66583012
8830864
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
1-hydroxymethyl-1-(trifluoromethyl)cyclobutane
C6H9F3O
154.13
≥97.0%(GC)
Colorless Clear Liquid
140-141°C
1g,5g,10g,25g,50g,100g and 500g
Store at room temperature
1-hydroxymethyl-1-(trifluoromethyl)cyclobutane is a useful trifluoromethylated cyclobutane building block for synthesis of various pharmaceutical compounds, e.g.  GPR119 agonists and SGLT2 inhibitors, etc..
Routes from 1,1-cycloalkanedicarboxylic acids to geminal bis(polyfluoromethyl) substituted carbocycles. [1]
Reference:
[1] A.Wolniewicz, J. F. Chem., 2001, 109(2), pp 95-102.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H301,H319
P301+P310,P305+P351+P338
2916.20.5000
UN 2810 6.1/PG III

1. Product Specification
2. Safety Data Sheet
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