2-bromo-3-fluoro-6-methylpyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-bromo-3-fluoro-6-picoline
Fluorinated Building Blocks
KUMI1F109
374633-36-0
MFCD03095061
24820318
18506793
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
2-bromo-3-fluoro-6-methylpyridine
C6H5BrFN
190.01
≥98%
White Solid
62-64°C
5g,10g,50g,100g,200g and 500g
Store at 2-8°C temperature
2-bromo-3-fluoro-6-methylpyridine is a fluorinated heterocyclic building block for the synthesis of various pharmaceutial compounds. Such as Plasmodium falciparum Calcium-Dependent Protein Kinase 1(PfCDPK1) inhibitors, macrocyclic factor XIa (FXIa) inhibitors, etc..
Optimization of an Imidazopyridazine Series of Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 (PfCDPK1). [1]
Synthesis and biological evaluation of 5-(fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles as inhibitors of transforming growth factor-β type I receptor kinase. [2]
Macrocyclic factor XIa inhibitors. [3]
References:
[1] T.M.Chapman, et al, J. Med. Chem., 2014, 57(8), pp 3570-3587.
[2] M.Krishnaiah, et al, Bioorg. Med. Chem. Lett., 2015, 25(22), pp 5228-5231.
[3] C.Wang, et al, Bioorg. Med. Chem. Lett., 2017, 27(7), pp 4056-4060.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302
P264,P270,P301+P312+P330,P501
2933499090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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