2-(2,2,2-Trifluoroethoxy)benzoic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-(2,2,2-tris(fluoranyl)ethoxy)benzoic acid
Trifluoroethoxylated Building Blocks
KUMI3F191
35480-46-7
MFCD08556302
11528644
2842274
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-(2,2,2-Trifluoroethoxy)benzoic acid
C9H7F3O3
220.15
≥97%
White to Yellow Solid
85-86°C
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at room temperature
2-(2,2,2-Trifluoroethoxy)benzoic acid is a useful trifluoroethoxylated building block for the preparation of various pharmaceutical compounds of interest, such as Flecainide acetate, which is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).
Palladium-Catalyzed C-H Trifluoroethoxylation of N-Sulfonylbenzamides. [1]
Reference:
[1] L.Yang, et al, Org. Lett., 2017, 19(10), pp 2746-2749.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P260,P280,P301+P312,P302+P352,P304+P340,P305+P351+P338
29189990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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