2,6-dichloro-3-(trifluoromethyl)pyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,6-bis(chloranyl)-3-(trifluoromethyl)pyridine
Trifluoromethyl Building Blocks
KUMI3F123
55304-75-1
MFCD00042245
1810337
1570287
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
2,6-dichloro-3-(trifluoromethyl)pyridine
C6H2Cl2F3N
215.98
≥98%
Colorless to Pale-yellow Liquid
194-196°C
5g,10g,25g,50g and 100g
Store at room temperature
2,6-dichloro-3-(trifluoromethyl)pyridine is a trifluoromethylated building block for the synthesis of various pyridine derivatives used as key pharmacetucial intermediates.
Synthesis of N-(trifluoromethyl-2-pyridinyl)arenesulfonamides as an inhibitor of secretory phospholipase A₂. [1]
A practical preparation of methyl 2-methoxy-6-methylaminopyridine-3-carboxylate from 2,6-dichloro-3-trifluoromethylpyridine. [2]
Synthesis of 2,6-diaryl-3-(trifluoromethyl)pyridines by regioselective Suzuki–Miyaura reactions of 2,6-dichloro-3-(trifluoromethyl)pyridine. [3]
References:
[1] H.Nakayama, et al, Chem. Pharm. Bull.(Tokyo), 2011, 59(6), pp 783-786.
[2] T.Horikawa, et al, Chem. Pharm. Bull.(Tokyo), 2011, 49(12), pp 1621-1627.
[3] S.Ahmed, et al, Tetrahedron Lett., 2013, 54(13), pp 1669-1672.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H300,H315,H319,H335
P261,P264,P301+p310,P305+P351+p338
2933399990
UN 2810 6.1/PG III

1. Product Specification
2. Safety Data Sheet
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