2-[6-(trifluoromethyl)pyridin-2-yl]acetic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-[6-(trifluoromethyl)pyridin-2-yl]ethanoic acid
Trifluoromethyl Building Blocks
KUMI3F115
1000565-32-1
MFCD09924928
53401513
21981675
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-[6-(trifluoromethyl)pyridin-2-yl]acetic acid
C8H6F3NO2
205.13
≥97%
Pale-yellow to Yellow Solid

5g,10g,25g,50g and 100g
Store at room temperature
2-[6-(trifluoromethyl)pyridin-2-yl]acetic acid is a pharmaceutically useful building block for the synthesis of various substituted indoline derivatives, such as inhibitors of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) for the treatment of cancer and diseases associated with activated unfolded protein response pathways.
Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development. [1]
Reference:
[1] J.M.Axten, et al, ACS Med. Chem. Lett., 2013, 4(10), pp 964-968.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302+H332,H315,H319,H335
P271,P260,P280
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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