2-bromo-3-(trifluoromethyl)-pyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-bromo-3-trifluoromethylpyridine
Trifluoromethyl Building Blocks
KUMI3F114
175205-82-0
MFCD00153084
5193820
8900385
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-bromo-3-(trifluoromethyl)-pyridine
C6H3BrF3N
225.99
≥97%
White to Pale-yellow Solid
37-41°C
5g,10g,25g,50g and 100g
Store at room temperature
2-bromo-3-(trifluoromethyl)-pyridine is an useful building block for the synthesis of various Pharmaceutical compounds. e.g. cholesteryl ester transfer protein (CETP) inhibitors, NaV1.7 inhibitors, etc..
Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein. [1]
Recommendable Routes to Trifluoromethyl‐Substituted Pyridine‐ and Quinolinecarboxylic Acids. [2]
Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors. [3]
References:
[1] M.A.Massa, et al, Bioorg. Med. Chem. Lett., 2001, 11(13), pp 1625-1628.
[2] F.Cottet, et al, Eur. J. Org. Chem., 2003, 8, pp 1559-1568.
[3] L.B.Schenkel, et al, Bioorg. Med. Chem. Lett., 2017, 27(16), pp 3817-3824.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H228,H300,H315,H318,H335
P210,P261,P264,P280,P301+P310,P305+P351+P338
2933399990
UN 2926 6.1(4.1)/PG III

1. Product Specification
2. Safety Data Sheet
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