2-(trimethylsilyl)ethyl 4-(trifluoromethylsulfonyloxy)-5,6-dihydropyridine-1(2H)-carboxylate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN

Trifluoromethyl Building Blocks
KUMI3F66
375854-77-6
MFCD16039327
60114393
10100577
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
2-(trimethylsilyl)ethyl 4-(trifluoromethylsulfonyloxy)-5,6-dihydropyridine-1(2H)-carboxylate
C12H20F3NO5SSi
375.43
≥95.0%
Light Yellow Liquid

500mg,1g,5g,10g,25g and 50g
Store at room temperature
2-(trimethylsilyl)ethyl 4-(trifluoromethylsulfonyloxy)-5,6-dihydropyridine-1(2H)-carboxylate is a biologically useful trifluoromethylated building block for synthesis of inhibitors of mast cell tryptase for treatment and amelioration of inflammatory diseases.
Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase. [1]
Reference:
[1] J.Levell, et al, Bioorg. Med. Chem., 2005, 13(8), pp 2859-2872.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H317,H319
P280,P305+P351+P338

NONH for all modes of transport

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