3,3,3-trifluoro-2-methylpropan-1-ol

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3,3,3-tris(fluoranyl)-2-methyl-propan-1-ol
Trifluoromethyl Building Blocks
KUMI3F80
431-23-2
MFCD20483912
10148993
1736199
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
3,3,3-trifluoro-2-methylpropan-1-ol
C4H7F3O
128.09
≥98.0%
Colorless to Light-yellow Liquid
108.5-109.5°C
1g,5g,10g,25g,50g,100g and 500g
Store at room temperature
3,3,3-trifluoro-2-methylpropan-1-ol is a useful trifluoromethylated building block for the synthesis of various pharmaceutically active compounds, such as Protein kinase modulators, particularly for aurora kinase and JAK kinase activity.
Novel Nucleophilic Trifluoromethylation of Vicinal Diol Cyclic Sulfates. [1]
The first one-pot synthesis of 1,3-dicarbonyl adamantanes from 1-bromoadamantanes. [2]
References:
[1] N.Takechi, et al, Org. Lett., 2002, 4(26), pp 4671-4672.
[2] I.S.Akhrem, et al, Mendeleev Commun., 2011, 21(5), pp 259-261.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H314
P280,P305+P351+P338,P310

UN 3265 8/PG III

1. Product Specification
2. Safety Data Sheet
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