3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Sitagliptin Triazole Impurity
Trifluoromethyl Building Blocks
KUMI3F45
486460-21-3
MFCD08460920

9848226
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
C6H7F3N4
192.14
≥98.0%(HPLC)
Pale yellow to Brown Solid
>260°C
5g,10g,50g,100g,500g and1kg
Store at 2-8°C(recommended)
3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (also known as Sitagliptin Triazole Impurity) is an intermediate in the synthesis of Sitagliptin,which is an oral antihyperglycemic (antidiabetic drug) of the dipeptidyl peptidase-4 (DPP4) inhibitor class. This drug was developed and marketed by Merck & Co. for the treatment of diabetes mellitus type2.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261

NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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