3-(trifluoromethyl)azetidine-3-ol hydrochloride is a useful trifluoromethylated azetidine building block for the synthesis of various pharmaceutical compounds, e.g. MDM2 inhibitors, HCV NS5B inhibitors and other antibacterial agents, etc..
Benzoxaborole Antimalarial Agents.Part 5.Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
 Y.Zhang, et al, J. Med. Chem., 2017, 60(13), pp 5889-5908.