4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3-(4-formylphenyl)-3-(trifluoromethyl)diazirine
Trifluoromethyl Building Blocks, Photoreactive Probe Building Blocks
KUMI3F58
128886-88-4
MFCD22683681
11333359
3547345
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde
C9H5F3N2O
214.15
≥98.0%(HPLC)
Pale yellow to Yellow Clear Liquid
>200°C
1g,2g,5g,10g,50g and 100g
Amber Vial, -20˚C Freezer, Under Inert Atmosphere
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde is an useful aldehyde intermediate and photoreactive probe building block for photaffinity labeling to study ligand–receptor, ligand–enzyme and protein–protein interactions, and in the isolation and identification of unknown proteins.
A new cleavable carbene-generating reagent with 3-phenyl-3-trifluoromethyldiazirine photophore. [1]
Simple and Versatile Method for Tagging Phenyldiazirine Photophores. [2]
Diazirine based photoaffinity labeling. [3]
References:
[1] Y. Hatanaka, U. Kempin, Y. Kanaoka, Heterocycles, 1998, 49(1), pp 464-468.
[2] H. Nakashima, M. Hashimoto, Y. Sadakane, T. Tomohiro, Y. hatanaka, J. Am. Chem. Soc., 2006, 128(47), pp 15092-15093.
[3] L. Dubinsky, B. P. Krom, M. M. Meijler, Bioorg. Med. Chem., 2012, 20(2), pp 554-570.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H227,H315,H319
P210,P264,P280,P302+P352+P332+P313+P362+P364,P305+P351+P338+P337+P313,P403+P235
2933.99.9701
NONH for all modes of transport

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