4-trifluoromethyl-4-hydroxypiperidine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
4-(Trifluoromethyl)piperidin-4-ol
Trifluoromethyl Building Blocks
KUMI3F99
373603-69-1
MFCD13179174
17951321
14455589
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4-trifluoromethyl-4-hydroxypiperidine
C6H10F3NO
169.15
≥98%
White to Light-yellow Solid

5g,10g,25g,50g,100g,250g and 500g
Store at room temperature
4-trifluoromethyl-4-hydroxypiperidine is an important building block for the synthesis of various pharmaceutical compounds, such as inhibitors of 11β-hydroxysteroid dehydrogenase type 1(11β-HSD1) and MCH receptor 1 antagonists, and so on.
Synthesis and biological evaluation of picolinamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1(11β-HSD1). [1]
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414. [2]
References:
[1] J.H.Ryu, et al, Bioorg. Med. Chem., 2015, 25(3), pp 695-700.
[2] S.G.Muller, et al, Bioorg. Med. Chem., 2015, 25(16), pp 3264-3269.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P264,P280,P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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