5-Hydroxy-5-(trifluoromethyl)oxolan-2-oneis a trifluoromethylated building block for the preparation of various compounds in organic synthesis.
Synthesis of indolizidine derivatives trifluoromethylated at bridgehead position via acyl iminium ion intermediates derived from ring-chain tautomerism of 5,5,5- trifluoro-4-oxopentanoyl arylethylamides. 
Nucleophilic trifluoromethylation of anhydrides employing (trifluoromethyl)trimethylsilane: Synthesis of γ-trifluoromethylated γ-butyrolactones. 
 T.Okano, et al, Heterocycles, 1997, 44(1), pp 227-236.
 C.Masusai, et al, J. F. Chem., 2013, 154, pp 37-42.
NONH for all modes of transport.
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