6-(Trifluoromethyl)pyridine-3-carboxylic acid 

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
6-trifluoromethylnicotinic acid
Trifluoromethylated Building Blocks
KUMI3F197
231291-22-8
MFCD00792430
2777551
9479539
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-(Trifluoromethyl)pyridine-3-carboxylic acid
C7H4F3NO2
191.11
≥97%
White to Beige Solid
193-197°C
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at room temperature
6-(Trifluoromethyl)pyridine-3-carboxylic acid (also named as 6-trifluoromethylnicotinic acid) is a useful trifluoromethylated building block for the preparation of various compounds of interest in pharmaceuticals and agrochemicals.
8-Piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines: Potent, selective, orally bioavailable 5-HT1 receptor ligands. [1]
Pyridine carboxamides: Potent palm site inhibitors of HCV NS5B polymerase. [2]
Exploration of N-(2-aminoethyl)piperidine-4-carboxamide as a potential scaffold for development of VEGFR-2, ERK-2 and Abl-1 multikinase inhibitor. [3]
Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase. [4]
References:
[1] T.D.Heightman, et al, Bioorg. Med. Chem. Lett., 2005, 15(19), pp 4370-4374.
[2] C.C.Cheng, et al, ACS Med. Chem. Lett., 2010, 1(9), pp 466-471.
[3] F.Jin, et al, Bioorg. Med. Chem., 2013, 21(8), pp 5694-5706.
[4] S.Ruf, et al, Bioorg. Med. Chem. Lett., 2018, 28(5), pp 922-925.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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