7-TFA-ap-7-Deaza-ddA

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine
Trifluorinated Building Blocks, Linkers for Gene(DNA) Sequencing
KUMI3F165
114748-71-9


3574197
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
7-TFA-ap-7-Deaza-ddA
C16H16F3N5O3
383.33
≥95%(HPLC)
White to Off-white Solid

5g,10g,25g,50g,100g,200g and 500g
Store at -20°C temperature
7-TFA-ap-7-Deaza-ddA (also named as 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine) is a trifluoromethyl-modified linker used for gene(DNA) sequencing and mapping.
Palladium-catalyzed synthesis of alkynylamino nucleosides. A universal linker for nucleic acids. [1]
Solvent, not palladium oxidation state, is the primary determinant for successful coupling of terminal alkynes with iodo-nucleosides. [2]
A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry. [3]
References:
[1] F.W.Hobbs, J. Org. Chem., 1989, 54(14), pp 3420-3422.
[2] M.J.Robins, et al, Tetrahedron Lett., 1990, 31(26), pp 3731-3734.
[3] N.K.Garg, et al, Chem. Commun., 2005, 36(0), pp 4551-4553.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a dangerous goods



NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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