(S)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN

Trifluoromethyl Building Blocks
KUMI6F16
1292282-19-9
MFCD28580130

21311555
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(S)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline
C13H7F6NO
307.19
≥97%
Light yellow to Yellow Solid
84°C
5g,10g,25g,50g,100g,250g and 500g
Store at room temperature
(S)-4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline is a trifluoromethlated intermediate for the preparation of some pharmaceutical active substances, such as mefloquine derivatives.
First enantioselective synthesis of 4-aminoalcohol quinoline derivatives through a regioselective SN2 epoxide opening mechanism. [1]
Reference:
[1] A.Jonet, et al, Tetrahedron: Asymmetry, 2011, 22(2), pp 138-148.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P271,P280
2933499090
NONH for all  modes of transport

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