3-Hydroxy-xanthen-9-one

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN 3582735
Sieber Linker
Bridge to Biologics, SPPS Linkers
KUMI0F467
3722-51-8
MFCD00604748
5376013
170775
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
3-Hydroxy-xanthen-9-one
C13H8O3
212.20
≥99%
White to Light Yellow Solid
254-255°C
5g,10g,50g,100g,500g, 1kg and 25kg
Store at 2-8°C temp.
 3-Hydroxy-xanthen-9-one (also named as Sieber Linker) is typically used as linker (linkage agent) in solid-phase peptide synthesis (SPPS).
 Preparation and applications of xanthenylamide (XAL) handles for solid-phase synthesis of C-terminal peptide amides under particularly mild conditions. [1]
 Synthesis, SAR and biological evaluation of natural and non-natural hydroxylated and prenylated xanthones as antitumor agents. [2]
 Xanthone conjugated amino acids as potential anticancer and DNA binding agents: Molecular docking, cytotoxicity and SAR studies. [3]
 References:
[1] Y.Han, et al, J. Org. Chem., 1996, 61(18), pp 6326-6339.
[2] X.Zhang, et al, Med. Chem., 2012, 8(6), pp 1012-1025.
[3] K.P.Rakesh, et al, Anticancer Agents Med. Chem., 2018, 18(15), pp 2169-2177.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
2932997000
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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