4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (also known as Pomalidomide-C3-NH2) is typically used as a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker for in the synthesis of proteolysis-targeting chimera (PROTAC) technologies.

 Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. [1]

 Reference:

[1] N.Shibata, et al, J. Med. Chem., 2018, 61(2), pp 543-575.