4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN 3582735
Pomalidomide-C3-NH2
Bridge to Biologics, Precursor for PROTACs
KUMI0F410
2093388-20-4
 
131999668
31896342
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
C16H18N4O4
330.34
≥98%
White to Off-White Solid
 
5g,10g,50g,100g,500g and 1kg
Store at 2-8°C temp.
  4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (also known as Pomalidomide-C3-NH2) is typically used as a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker for in the synthesis of proteolysis-targeting chimera (PROTAC) technologies.
 Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. [1]
 Reference:
[1] N.Shibata, et al, J. Med. Chem., 2018, 61(2), pp 543-575.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
29339900
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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